CAMM Assays & Services for
Pharmacodynamic Analysis in Bacterial Diseases
RS ratio™️*
A novel molecular readout of the effect of drugs and drug combinations on bacterial cellular processes. By providing information that complements traditional culture-based enumeration, the RS ratio is transforming in vitro, in preclinical and human studies.
CAMM provides RS ratio collection kits and performs RS ratio profiling in a quality-assured workflow in the CAMM Molecular Core.
* For Research Use Only
Act-TB*
An multi-metric activity-based TB drug analysis approach, named Act-TB, is used to comprehensively evaluate the effect of drugs on the physiologic state and cellular processes of M. tuberculosis in vitro.
* For Research Use Only
SEARCH-TB*
SEquencing after Amplicon enRiCHment for TB. A targeted method of quantifying the M. tuberculosis transcriptome at low bacterial abundance in animal treatment models
* For Research Use Only
Knowledge Integration
Systems pharmacology and PK/DP modeling harness established and novel PD markers to maximize insight